Do You Know PVP In Disinfection And Sterilization

PVP with CAS 9003-39-8 is a non-ionic polymer formed by the polymerization of N-vinylpyrrolidone (NVP) under certain conditions. Polyvinylpyrrolidone is one of the important excipients advocated internationally.

PVP is a white to milky white powder. Easily soluble in water, alcohol, amines and halogenated hydrocarbons, but insoluble in acetone, ether, etc. It has excellent solubility, biocompatibility, physiological inertness, film-forming properties, film protection ability and the ability to combine various organic and inorganic compounds, and is relatively stable to acids, salts and heat. Therefore it has a wide range of uses.

PVP can be divided into industrial grade, pharmaceutical grade, food grade and cosmetic grade according to different application fields. PVP products use K value to characterize the average molecular weight of PVP. Generally, the larger the K value, the greater the viscosity and the stronger the adhesion. In fact, K value is a characteristic value related to the relative viscosity of PVP aqueous solution.

pvp CAS 9003-39-8-content-pic

Although PVP itself has no bactericidal effect, it is widely used in the field of disinfection and sterilization. PVP has excellent ability to complex small molecules, PVP fungicides are PVP and antibacterial substances to form complexes, the common is povidone iodine (PVP-I). This complex maintains the broad spectrum bactericidal effect of iodine, and iodine is released from PVP polymer during use. Due to the affinity of PVP to cell membrane, iodine can directly lead to the bacterial cell surface to play the original bactericidal effect. The attack target of iodine is bacterial cytoplasm and cytoplasmic membrane, and it will kill many types of bacteria, fungi and viruses very quickly. At the same time, it can avoid the allergic reaction of the skin and solve the instability and irritation of the iodine solution.

At present, PVP disinfectant has been widely used in the field of medical and health surgery, medical equipment, wound disinfection, burn treatment, ulcer and all kinds of human skin and mucous membranes disinfection and sterilization work; In laboratory research, it can be used to disinfect and sterilize laboratory instruments, petri dishes and reagent bottles, etc. Contamination by bacteria and other microorganisms may affect the accuracy of experimental results; It is used in food and catering hygiene for food preservation, disinfection of catering industry, disinfection of food processing places, disinfection of refrigerators, etc.; In the aquaculture industry for the treatment of fish, shellfish, shrimp, crab disease prevention and treatment, in livestock and poultry breeding disinfection and disease treatment also have obvious effects. And gradually replace the traditional iodine and chlorine and mercury containing fungicides.

The advantages of PVP (polyvinylpyrrolidone) in disinfection and sterilization include:

1.High safety: compared with glutaraldehyde, PVP is less harmful to the human body and the environment during use.

2.Non-toxic: PVP does not contain toxic substances and will not cause irritation or damage to the human body.

3.Antibacterial properties: PVP can form complexes and has adsorption capacity, which can adsorb bacteria and other microorganisms, thereby reducing their number on the skin surface, thereby enhancing the effect of antibacterial substances.

In all, PVP has been widely used in disinfection and sterilization field by virtue of its properties. Unilong can supply PVP with high quality, competitive price and superior service.

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